Edventures in Normalcy

Edgecast Rules based on Hostname or IP Address, only if you have a common naming convention for the Directory Name, for example:

prefix1_example.net
prefix2_example.org

You can then create a rule:
IF ‘URL Path Directory’ ‘Matches’ Value:
/123456/prefix1_* (I used 123456 in place of the CDN origin path, update this to your settings) ‘Ignore Case’, ‘Relative To’:’Root’
then you can group by prefix on folder name, and have rules for them that way.